Application of allicin in aquaculture

Allicin is a green drug-type feed additive with no side effects and no pollution to the environment. It is used in aquaculture to improve the palatability of feed, promote appetite, stomach and bactericidal, deworming and health care, and promote growth. There is no accumulation, no drug resistance in the body, no side effects such as teratogenicity, carcinogenesis, mutagenicity, etc., and it is widely used in disease prevention and treatment. XUc China Feed Industry Information Network - based on feed, serving animal husbandry

1, the advantages of allicin XUc China feed industry information network - based on feed, service animal husbandry

1.1 Wide range of applications XUc China Feed Industry Information Network - based on feed, serving animal husbandry

Allicin has a broad-spectrum antibacterial effect, can prevent and cure a variety of common infectious diseases, can improve the body's immunity, can be used in livestock, poultry, fish and some special economic animal breeding, and can be used in all stages of animal growth. XUc China Feed Industry Information Network - based on feed, serving animal husbandry

1.2 No use contraindications XUc China Feed Industry Information Network - based on feed, serving livestock

Allicin can be used in combination with other additives, including antibiotics, without antagonism or restriction of withdrawal. It can be used before the market for livestock and poultry products. XUc China Feed Industry Information Network - based on feed, serving animal husbandry

1.3 High safety XUc China Feed Industry Information Network - based on feed, serving animal husbandry

As a non-drug growth-promoting agent, allicin has a very low residual amount in animals. Routine tests have not been detected in muscle and liver, no drug resistance, and no carcinogenic, teratogenic or mutagenic effects. long-term use. XUc China Feed Industry Information Network - based on feed, serving animal husbandry

1.4 Multiple effects XUc China Feed Industry Information Network - based on feed, serving animal husbandry

Allicin not only has the effect of sterilization and attracting food, but also improves the quality of livestock and poultry products and improves the feeding environment. XUc China Feed Industry Information Network - based on feed, serving animal husbandry

2, the function of allicin XUc China feed industry information network - based on feed, service animal husbandry

2.1 Antibacterial and anti-inflammatory effects XUc China Feed Industry Information Network - based on feed, serving animal husbandry

Allicin has strong antibacterial and anti-inflammatory effects, and it has inhibitory or killing effects on various cocci, bacilli (dysentery, typhoid, large intestine, whooping cough), fungi and viruses. Zhang Wei studied the pharmacodynamics of allicin to two strains of Aeromonas hydrophila in aquatic animals. The results showed that allicin had a certain antibacterial effect on Aeromonas hydrophila. XUc China Feed Industry Information Network - based on feed, serving animal husbandry

2.2 Detoxification XUc China Feed Industry Information Network - based on feed, serving animal husbandry

Allicin inhibited the increase of serum GPT and MDA levels induced by CCl4-induced liver injury in rats. Garlic also increases the activity of glutathione S-transferase in mouse hepatocytes, thereby improving liver detoxification and preventing mercury, cadmium, lead and other poisoning. XUc China Feed Industry Information Network - based on feed, serving animal husbandry

2.3 Enhance immune function XUc China Feed Industry Information Network - based on feed, service animal husbandry

Allicin can inhibit the production of nitric oxide by macrophages, thereby promoting the activation of T lymphocytes and improving cellular immune function. On the other hand, the antibody specifically binds to the exotoxin so that it does not produce toxic effects and significantly enhances humoral immune function. Allicin can also activate the secretion level of monocytes, and promote the release of lysozyme, thereby hydrolyzing the sticky polypeptide in the cell wall to kill bacteria and enhance non-specific immune function. XUc China Feed Industry Information Network - based on feed, serving animal husbandry

3, the application of allicin XUc China feed industry information network - based on feed, service animal husbandry

3.1 As a fish disease prevention and treatment drug XUc China Feed Industry Information Network - based on feed, serving animal husbandry

A large number of studies have shown that allicin can effectively kill the main pathogens of freshwater fish such as Bacillus fluorescens, Mycobacterium sphaeroides, Vibrio anguillarum, Edwards, Aeromonas, and Ryerson, and grass carp. Enteritis, rotten rot, red skin disease and squid bleeding and fish fulminant infectious diseases are particularly effective, and are currently one of the better drugs for the prevention and treatment of fish diseases. XUc China Feed Industry Information Network - based on feed, serving animal husbandry

Oral administration can prevent bacterial rot disease and enteritis disease. The medicated bath method can prevent and treat vertical squamous disease. The whole pool splashing method can prevent enteritis, rot, and red skin disease, and has good therapeutic effects on the complications of these diseases. . Jia Weibin and other reports, adding 100mg/kg of synthetic allicin to the carp bait, the survival rate of carp increased by 2.5% compared with the control group; adding 50mg/kg, lOOmg/kg synthetic allicin to the carp in the bait, and the control group Compared with the survival rate of soft-shelled turtles, they increased by 2.44% and 2.96% respectively; adding 1% garlic to the feed can control the red leg disease of shrimp; adding 5% of garlic for cage cultured salmon, the survival rate increased by 2.16%; adding 0.008 % garlic oil can increase the survival rate of grass carp by more than 15%. Tang Xuerong and others believe that garlic thiamine (a compound of allicin and thiamine) can inhibit the action of thiamine enzyme, can significantly enhance the resistance of shrimp, and greatly reduce the mortality: Fu Tonglu and other added 1% in grass carp and carp bait Garlic slag premix, the survival rate of carp increased by more than 15%; Yan Jie in the lOOha pond test found that allicin has a good control effect on fish susceptible to enteritis, rot disease, and no toxic side effects. XUc China Feed Industry Information Network - based on feed, serving animal husbandry

3.2 Aquaculture Feed Additives XUc China Feed Industry Information Network - Based on Feed, Serving Livestock

Allicin is a natural and environmentally friendly green feed additive that promotes growth in aquatic animals and improves feed utilization. Freshwater white carp feeding test was carried out by adding 25, 50, 75, 100 mg/kg of allicin to the feed. After 40 days, compared with the control group, the weight gain rate of each test group increased by 57.49%, 91.25%, 101.26% and 87.74%, respectively, and the survival rate increased by 8.13%, 2.09%, 7.50%, 14.59%, respectively, and the feed coefficient decreased. 8.79%, 12.13%, 9.62% and 1.67%, the crude protein content in the muscles of the experimental group increased by 3.82%, 6.00%, 17.69%, 18.38%, respectively, and the crude fat content decreased by 5.74%, 3.95%, 2.75%, respectively. And 1.24%. Chen Xinran added allicin to the feed to feed the carp. It was found that allicin significantly increased the growth rate of the cultured carp. Adding allicin to the bullfrog feed can promote the growth of bullfrogs, reduce the feed coefficient, increase the survival rate, thereby reducing the cost of raising frogs and improving economic benefits (Hu Shiliang et al., 2000). Wu Li et al added the appropriate amount of betaine and allicin to the feed. The test showed that the two could significantly enhance the protease activity of the channel squid, and both additives can significantly promote the growth of the fish, especially adding garlic. The group of fish has the fastest growth rate. XUc China Feed Industry Information Network - based on feed, serving animal husbandry

Allicin has a feeding effect on aquatic animals and can increase the food intake of animals. For example, adding 50 mg/kg of allicin to tilapia feed, after 45 days of feeding, found that allicin has a strong attracting effect, and tilapia shows the characteristics of eating and eating fast. XUc China Feed Industry Information Network - based on feed, serving animal husbandry

Allicin contains various thioether compounds. Long-term feeding can reduce fish cholesterol and improve the meat quality of aquatic animals. Lin Yibin believes that long-term feeding of allicin can enhance the flavor of fish. Japanese experts add 50mg/kg of allicin powder to fish feed such as rainbow trout, real clam and gingiva. After long-term uninterrupted feeding, the meat of the adult fish is fine and compact, and the fish is delicious and fragrant. Under the condition of stopping for 3 weeks, the muscle strength of the fish body was 1.2 times of that of the control group, and the muscle strength of the fish was increased by 1.5 times after 6 weeks of rest. The muscle fiber thickness of the test fish was about half of that of the control group, and the fat percentage in the fish body decreased. 1.8%. According to Japanese reports, crushing garlic and squeezing 1OOg, adding 0.5%-3% VB1, reacting at 50-70 ° C for 1-7 hours to obtain garlic thiamine solution, then adding 0.5% binder and 2 % of VB1 is made into a bait additive, and then it is used to feed the juvenile. After one year, not only the weight gain rate of the cockroach is increased by about 20%, but also the odor of the cockroach has disappeared (Zhang Ning, 1999). XUc China Feed Industry Information Network - based on feed, serving animal husbandry

Allicin can also effectively prevent the mildew of feed. It not only kills germs, but also kills various molds. The special smell of allicin can also drive fly maggots and prevent feed deterioration. XUc China Feed Industry Information Network - based on feed, serving animal husbandry

4, the rational application of allicin XUc China feed industry information network - based on feed, service animal husbandry

Although allicin has a good effect, it should be used reasonably. Do not blindly increase the dosage to avoid waste or even adverse effects. Huang Xingguo et al. conducted a preliminary study on the application effect of allicin in Astragalus membranaceus. The results showed that the survival rate and disease control effect were different due to different doses of allicin in different feeding stages: no feeding period was added, and feeding was carried out for 1 month. After the survival rate was 89%, the cause of death was mainly red skin disease and enteritis; the addition of 200mg/kg and 400mg/kg allicin in the compound feed, the stage survival rate was 95% and 94%, respectively, the mortality was reduced, and the survival rate was improved. There is no red skin disease and enteritis. This indicates that the addition of 200mg/kg and 400mg/kg allicin in the compound feed will not only have a toxic effect on the jaundice, but also have a certain effect on the prevention and treatment of the disease and the improvement of the survival rate. However, at the concentration of 800 mg/kg allicin, all died within 3 days, indicating that the concentration was too high to have a toxic effect on jaundice. XUc China Feed Industry Information Network - based on feed, serving animal husbandry

When adding allicin to the feed, the appropriate dosage should be determined according to the type of animal and the characteristics of different growth stages, combined with the effective content of allicin, as well as the ratio of raw materials and actual needs. The general aquafeed has a good effect on the application of 25% allicin 100g/T. If you want to have better attracting properties, you should apply more than 150g; if the feed contains antioxidants and mildew inhibitors, as well as rapeseed meal, meat and bone meal, etc., you should increase the dosage if you have better attracting effect. XUc China Feed Industry Information Network - based on feed, serving animal husbandry

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